KMID : 0363220080460101376
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Korean Journal of Dermatology 2008 Volume.46 No. 10 p.1376 ~ p.1380
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A Case of Microcystic Adnexal Carcinoma on the Scalp
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Ju Hye-Young
Kim Si-Yong Kim Gyong-Moon Kang Seok-Jin
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Abstract
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Microcystic adnexal carcinoma is a rare, locally aggressive tumor with a high potential for local recurrence. It
usually presents in elderly patients as a solitary, slowly growing, firm, indurated plaque on the face, and particularly
on the upper lip or central face. It has occasionally been found in extra-facial locations, including the nipple, axilla
and lower extremities, yet scalp involvement has been rarely reported. Histopathologically, it is a poorly
circumscribed dermal tumor that shows both follicular and ductal differentiation, and it may extend into the subcutis
and skeletal muscle. We report here on a case of microcystic adnexal carcinoma at an unusual site: the scalp. A
42-year-old woman presented with a 6-month history of a painful, solitary, 1 cm-sized, firm, fixed, dome-shaped
nodule on the scalp, and this was accompanied by ulceration and oozing. A biopsy specimen demonstrated features
of microcystic adnexal carcinoma, with both follicular and ductal differentiation. Immunohistochemical staining for
CEA (carcinoembryonic antigen) was positive in the ductal structures, but this was negative in the follicular structures.
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KEYWORD
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Microcystic adnexal carcinoma, Scalp
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